This Article Full Text (PDF) References Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Add to Saved Citations Download to citation manager Request Permissions Request Reprints Add to My Marked Citations Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Citing Articles via Scopus Google Scholar Articles by Yusuf, S. Articles by Camm, A. J. Search for Related Content PubMed PubMed Citation Articles by Yusuf, S. Articles by Camm, A. J. Pubmed/NCBI databases Compound via MeSH Substance via MeSH Hazardous Substances DB CLONIDINE VERAPAMIL HYDROCHLORIDE Social Bookmarking                         What's this?

Sinus Tachyarrhythmias and the Specific Bradycardic Agents: A Marriage Made in Heaven?

A. John Camm, MD

Department of Cardiovascular Medicine, St. Georges Hospital Medical School, London, UK

A relatively novel group of drugs that inhibit the funny current in the sinus node pacemaker cells, the so-called specific bradycardic agents, are likely to play a significant role in the management of a wide range of cardiovascular disorders, including the sinus tachyarrhythmias. This comprehensive review initially provides an insight into these agents, their historical background, and their mechanism of action. It then discusses the differential diagnosis of the sinus tachyarrhythmias (normal sinus tachycardia, inappropriate sinus tachycardia, postural orthostatic tachycardia syndrome, and sinus node reentry tachycardia), elaborates on their pathophysiologic basis, and provides up-to-date evidence-based information on their optimum management. The specific bradycardic agents, by the very nature of their mode of action, may prove ideal therapies for the management of the sinus tachyarrhythmias, and this is explored at every stage.

Key Words: inappropriate sinus tachycardia • postural orthostatic tachycardia syndrome • sinus node reentry tachycardia

Journal of Cardiovascular Pharmacology and Therapeutics, Vol. 8, No. 2, 89-105 (2003)
DOI: 10.1177/107424840300800202


CiteULike    Complore    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter    What's this?

This article has been cited by other articles:

				P. K. Mason and J. P. DiMarco New Pharmacological Agents for Arrhythmias Circ Arrhythm Electrophysiol, October 1, 2009; 2(5): 588 - 597. [Full Text] [PDF]