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Journal of Cardiovascular Pharmacology and Therapeutics
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Plasma Levels of Brain Natriuretic Peptide: A Potential Marker for HIV-Related Cardiomyopathy

Rodolfo Carrillo-Jimenez, MD

Department of Cardiology, Mount Sinai Medical Center Miami Beach, FL

Gervasio A. Lamas, MD

Department of Cardiology, Mount Sinai Medical Center Miami Beach, FL; Department of Medicine, University of Miami School of Medicine

Charles H. Hennekens, MD, DrPH

Department of Cardiology, Mount Sinai Medical Center Miami Beach, FL; Department of Medicine, University of Miami School of Medicine; Department of Epidemiology and Public Health, University of Miami School of Medicine

One of the most common and life-threatening cardiovascular complications of HIV-infection is severe global left ventricular dysfunction due to primary heart muscle disease. At present, there is no single, cost-effective and reliable method of identifying the highly prevalent HIV-related cardiac dysfunction. Nonetheless, growing evidence supports the hypothesis that brain natriuretic peptide measurement has the potential to detect patients who develop HIV-related cardiomyopathy. If true, this hypothesis would have important clinical and public health implications.

Key Words: echocardiography • AIDS • heart failure • screening.

Journal of Cardiovascular Pharmacology and Therapeutics, Vol. 7, No. 3, 135-137 (2002)
DOI: 10.1177/107424840200700302
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