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Journal of Cardiovascular Pharmacology and Therapeutics, Vol. 12, No. 2, 85-88 (2007)
DOI: 10.1177/1074248407302764

Brain Natriuretic Peptide: Clinical and Research Challenges

Rodolfo Carrillo-Jimenez, MD

Bethesda Memorial Hospital Boynton Beach

Steven Borzak, MD

Nova Southeastern College of Medicine Ft. Lauderdale, Charles E. Schmidt College of Science Florida Atlantic University, Boca Raton

Charles H. Hennekens, MD, DPH

Nova Southeastern College of Medicine Ft. Lauderdale, Charles E. Schmidt College of Science Florida Atlantic University, Boca Raton, University of Miami Miller School of Medicine Miami, Florida

Natriuretic peptides, in particular, brain or B-type, are useful for the assessment of patients presenting with dyspnea to the medical office or emergency department. Levels of natriuretic peptides are useful for assessing prognosis of heart failure or coronary syndrome patients. Less is known about serial peptide measurements for guiding treatment strategies in heart failure. The authors review the uses, pitfalls, and practical points for using natriuretic peptides clinically.

Key Words: brain natriuretic peptide • heart failure • immunoassay


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